Adjuvant for Tolerogenic Immunization Cutting Edge: Immunosuppressant as
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Cutting edge: in vitro-generated tolerogenic APC induce CD8+ T regulatory cells that can suppress ongoing experimental autoimmune encephalomyelitis.
APC exposed to TGFbeta2 and Ag (tolerogenic APC) promote peripheral Ag-specific tolerance via the induction of CD8(+) T regulatory cells capable of suppressing Th1 and Th2 immunity. We postulated that tolerogenic APC might reinstate tolerance toward self-neuronal Ags and ameliorate ongoing experimental autoimmune encephalomyelitis (EAE). Seven days after immunization with myelin basic protein (...
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Experimental Study of the Effect of Laser-Cutting Process Parameters on Heat Distribution and Cutting Edge Quality of Steel Sheets
This study aimed to evaluate Laser-cutting process of Mild Steel St37 sheets with two different thicknesses. In order to evaluate the quality of cutting edge and the depth of the area affected by the heat, several tests were conducted to determine the effect of parameters such as Laser power, Laser beam movement speed and pressure of axillary gas on the quality of cutting edge and the depth of ...
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